- Johnny Depp Willy Wonka
- Freddie Highmore Charlie Bucket
- David Kelly El abuelo Joe
- Noah Taylor Papá Bucket
- Christopher Lee Dr. Wonka
- Helena Bonham Carter Mamá Bucket
- Missi Pyle Sra. Beauregarde
- James Fox Sr. Salt
- Deep Roy Oompa-Loompas
- Annasophia Robb Violet Beauregarde
- Liz Smith Abuela Georgina