- Emile Hirsch Jay
- Victor Rasuk Tony
- John Robinson Stacy
- Michael Angarano Sid
- Nikki Reed Kathy Alva
- Rebecca De Mornay Philaine
- Heath Ledger Skip
- Johnny Knoxville Topper Burks
- Sofía Vergara Amelia
- Ned Bellamy Peter Darling
- Shea Whigham Drake Landon
- Joel McHale Reportero TV
- Pablo Schreiber Charlie