- Claire Danes Ann Grant
- Toni Collette Nina Mars
- Vanessa Redgrave Ann Lord
- Patrick Wilson Harris Arden
- Hugh Dancy Buddy Wittenborn
- Natasha Richardson Constance Haverford
- Mamie Gummer Lila Wittenborn
- Eileen Atkins Enfermera
- Meryl Streep Lila Ross
- Glenn Close Sra. Wittenborn
- Barry Bostwick
- Ebon Moss-Bachrach Luc