- Richard Gere Paul
- Diane Lane Adrienne
- Scott Glenn Robert Torrelson
- Christopher Meloni Jack
- Viola Davis Jean
- Mae Whitman Amanda
- Charlie Tahan Danny
- Jessica Lucas Enfermera
- James Franco (sin acreditar)
- Carolyn McCormick Jenny Flanner
- Pablo Schreiber Charlie Torrelson
- Ato Essandoh Amante de Jean