- Meryl Streep Julia Child
- Amy Adams Julie Powell
- Stanley Tucci Paul Child
- Chris Messina Eric Powell
- Linda Emond Simone Beck
- Vanessa Ferlito Cassie
- Mary Lynn Rajskub Sarah
- Jane Lynch Dorothy McWilliams
- Casey Wilson Regina
- Helen Carey Louisette Bertholle
- Christelle Cornil
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