- Jeremy Renner Aaron Cross
- Rachel Weisz Dra. Marta Shearing
- Edward Norton Coronel Eric Byer
- Stacy Keach Almirante Turso
- Oscar Isaac Nº3
- Joan Allen Pam Landy
- Albert Finney Dr. Albert Hirsch
- David Strathairn Noah Vosen
- Scott Glenn Ezra Kramer
- Donna Murphy Dita Mandy
- Corey Stoll Zev Vendel
- Zeljko Ivanek Dr. Donald Foite
- Corey Johnson Ray Wills
- Robert Prescott Oficial Air Force
- Michael Chernus Arthur Ingram
- Ian Blackman Landy's Attorney
- Rob Yang C-Team
- John Douglas Thompson Lt. Gen. Paulsen