- Will Ferrell Cam Brady
- Zach Galifianakis Marty Huggins
- Jason Sudeikis Mitch
- Katherine LaNasa Rose Brady
- Dylan McDermott Tim Wattley
- John Lithgow Glen Motch
- Dan Aykroyd Wade Motch
- Brian Cox Raymond
- Sarah Baker Mitzi Huggins
- Thomas Middleditch Tripp
- P.J. Byrne Rick
- Madison Wolfe Jessica Brady