- Kristen Stewart Bella Swan
- Robert Pattinson Edward Cullen
- Taylor Lautner Jacob Black
- Billy Burke Charlie Swan
- Peter Facinelli Dr. Carlisle Cullen
- Nikki Reed Rosalie Hale
- Ashley Greene Alice Cullen
- Kellan Lutz Emmett Cullen
- Cam Gigandet James
- Jackson Rathbone Jasper Cullen
- Elizabeth Reaser Esme Cullen
- Edi Gathegi Laurent / vampiro nómada
- Rachelle Lefevre Victoria / vampiro nómada
- Anna Kendrick Jessica Stanley
- Gil Birmingham Billy Black
- Michael Welch Mike Newton
- Justin Chon Eric