- Julianne Moore Cathy Whitaker
- Dennis Quaid Frank Whitaker
- Patricia Clarkson Eleonor Fine
- Dennis Haysbert Raymond Deagan
- James Rebhorn Dr. Bowman
- Viola Davis Sybil
- Bette Henritze Mrs. Leacock
- Michael Gaston Stan Fine
- Ryan Ward David Whitaker
- Lindsay Andretta Janice Whitaker
- Jordan Puryear Sarah Deagan
- Kyle Timothy Smith Billy Hutchinson (como Kyle Smith)
- Celia Weston Mona Lauder
- Barbara Garrick Doreen
- Olivia Birkelund Nancy
Cinemanía > Películas > Lejos del cielo > Reparto