- Harry Connick Jr. Dr. Clay Haskett
- Ashley Judd Lorraine Nelson
- Nathan Gamble Sawyer Nelson
- Kris Kristofferson Reed Haskett
- Morgan Freeman Dr. Cameron McCarthy
- Ray McKinnon Sr. Doyle
- Austin Highsmith Phoebe
- Austin Stowell Kyle Connellan
- Cozi Zuehlsdorff Hazel Haskett