- Alden Ehrenreich Ethan Wate
- Alice Englert Lena Duchannes
- Jeremy Irons Macon Ravenwood
- Viola Davis Amma
- Emmy Rossum Ridley Duchannes
- Thomas Mann Link
- Emma Thompson Sra. Lincoln/Sarafine
- Kyle Gallner Larkin
- Margo Martindale Tía Del
- Eileen Atkins Gramma
- Pruitt Taylor Vince Sr. Lee
- Zoey Deutch Emily Asher
- Rachel Brosnahan Genevieve Duchannes