- Adam Sandler Lenny Feder
- Kevin James Eric Lamonsoff
- Chris Rock Kurt McKenzie
- David Spade Marcus Higgins
- Salma Hayek Roxanne Chase-Feder
- Maya Rudolph Deanne McKenzie
- Maria Bello Sally Lamonsoff
- Nick Swardson Nick
- Taylor Lautner Frat Boy Andy
- Steve Buscemi Wiley
- Andy Samberg Male Cheerleader
- Milo Ventimiglia Frat Boy Milo
- Alexander Ludwig Braden
- Jon Lovitz Squats Fitness Janitor
- Tim Meadows Malcolm
- Oliver Hudson Kyle
- Allen Covert Hippie Teacher
- David Henrie Frat Boy
- Halston Sage Nancy Arbuckle
- Colin Quinn Dickie Bailey
- Nadji Jeter Andre Mckenzie
- Patrick Schwarzenegger
- Taran Killam