- Tom Hanks Captain Richard Phillips
- Catherine Keener Andrea Phillips
- Barkhad Abdi Muse
- Barkhad Abdirahman Bilal
- Faysal Ahmed Najee
- Mahat M. Ali Elmi
- Michael Chernus Shane Murphy
- Max Martini Comandante SEAL
- Chris Mulkey John Cronan
- Yul Vazquez Frank Castellano
- David Warshofsky Mike Perry
- Corey Johnson Ken Quinn
- John Magaro Dan Phillips