- Eddie Redmayne Balem Abrasax
- Channing Tatum Caine Wise
- Mila Kunis Júpiter Jones
- Sean Bean Stinger Apini
- Douglas Booth Titus Abrasax
- Tuppence Middleton Kalique Abrasax
- Gugu Mbatha-Raw Famulus
- Maria Doyle Kennedy Aleksa
- Edward Hogg Chicanery Night
- Jeremy Swift Vasilliy Bolodnikov
- Tim Pigott-Smith Malidictes
- Samuel Barnett Advocate Bob
- James D'Arcy
- Doona Bae
- Terry Gilliam
- Ariyon Bakare Greeghan
- Vanessa Kirby Katharine Dunlevy
- Nikki Amuka-Bird Diomika Tsing
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