- John Cusack Ed
- Ray Liotta Rhodes
- Amanda Peet Paris
- John Hawkes Larry
- Alfred Molina Doctor
- Clea DuVall Ginny
- John C. McGinley George
- Lee Scott Lou William
- Jake Busey Robert Maine
- Pruitt Taylor Vince Malcolm Rivers
- Rebecca De Mornay Caroline Suzanne
- Matt Letscher Assistant District Attorney
