- Philip Seymour Hoffman Mickey Scarpato
- Christina Hendricks Jeanie Scarpato
- John Turturro Arthur 'Bird' Capezio
- Caleb Landry Jones Leon Hubbard
- Richard Jenkins Richard Shellburn
- Eddie Marsan Smilin' Jack Moran
- Jack O'Connell Mole Ferrell
- Domenick Lombardozzi Sal Cappi
- Glenn Fleshler Coleman Peets