- Christian Bale Dick Cheney
- Amy Adams Lynne Cheney
- Steve Carell Donald Rumsfeld
- Sam Rockwell George W. Bush
- Jesse Plemons Kurt
- Alison Pill Mary Cheney
- Eddie Marsan Paul Wolfowitz
- Justin Kirk Scooter Libby
- LisaGay Hamilton Condoleezza Rice
- Bill Camp Gerald Ford
- Don McManus David Addington
- Lily Rabe Liz Cheney
- Shea Whigham Wayne Vincent
- Stephen Adly Guirgis George Tenet
- Tyler Perry Colin Powell
- Casey Sander Old Crew Member
- Jillian Armenante Karen Hughes
- Roman Mitichyan Cleric