- John Goodman William Mulligan
- Ashton Sanders Gabriel Drummond
- Jonathan Majors Rafe Drummond
- Vera Farmiga Jane Doe
- Kevin Dunn Commissioner Eugene Igoe
- James Ransone Patrick Ellison
- Madeline Brewer Rula
- Machine Gun Kelly Jurgis
- Kevin J. O'Connor Kermode
- Ben Daniels Daniel
- KiKi Layne Carrie
- D.B. Sweeney Levitt
- Shannon Cochran Kathy Mulligan