- Dwayne Johnson Luke Hobbs
- Jason Statham Deckard Shaw
- Idris Elba Brixton Lorr
- Vanessa Kirby Hattie Shaw
- Helen Mirren Queenie Shaw
- Cliff Curtis Jonah Hobbs
- Eiza González Madam M
- Eddie Marsan Profesor Andreiko
- Joe Anoa'i Mateo Hobbs
- Rob Delaney Agent Loeb