- Saoirse Ronan Jo March
- Emma Watson Meg March
- Florence Pugh Amy March
- Eliza Scanlen Beth March
- Laura Dern Marmee March
- Timothée Chalamet Theodore 'Laurie' Laurence
- Tracy Letts Sr. Dashwood
- Bob Odenkirk Robert March
- Chris Cooper Mr. Laurence
- Meryl Streep Tía March
- James Norton John Brooke
- Louis Garrel Friedrich Bhaer
- Sasha Frolova Sra. Hummel
- Hadley Robinson Sallie Gardiner Moffat