- Bob Dylan Jack Fate
- John Goodman Uncle Sweetheart
- Jessica Lange Nina Veronica
- Luke Wilson Bobby Cupid
- Jeff Bridges Tom Friend
- Penélope Cruz Pagan Lace
- Ed Harris Oscar Vogel
- Angela Bassett Mistress
- Val Kilmer Animal Wrangler
- Giovanni Ribisi Soldier
- Mickey Rourke Edmund
- Christian Slater Crew Guy #1
- Chris Penn Crew Guy #2
- Steven Bauer Edgar
- Bruce Dern Editor
- Cheech Marin Prospero
- Noel Gugliemi
- Davenia McFadden Conductora autobús